World Library  
Flag as Inappropriate
Email this Article


Article Id: WHEBN0003637556
Reproduction Date:

Title: Meningoencephalitis  
Author: World Heritage Encyclopedia
Language: English
Subject: List of MeSH codes (C10), Encephalitis, Jamestown Canyon virus, Listeriosis, Meningitis
Collection: Central Nervous System Disorders, Encephalitis, Herpes Simplex Virus-Associated Diseases, Meningitis
Publisher: World Heritage Encyclopedia


Classification and external resources
ICD-10 G04
ICD-9-CM 323.9
DiseasesDB 22354
MeSH D888590

Meningoencephalitis (; from Greek: meninges- membranes; enkephalos brain; and -itis inflammation) is a medical condition that simultaneously resembles both meningitis, which is an infection or inflammation of the meninges, and encephalitis, which is an infection or inflammation of the brain.


  • Causes 1
    • Bacterial 1.1
    • Viral 1.2
    • Other/multiple 1.3
    • Protozoal 1.4
    • Animal 1.5
  • Prognosis 2
  • Notable cases 3
  • In popular culture 4
  • See also 5
  • References 6


Causative organisms include protozoans, viral and bacterial pathogens.

Specific types include:





Ameobic pathogens exist as free-living protozoans. Nevertheless, these pathogens cause rare and uncommon CNS infections. N. fowleri produces primary amebic meningoencephalitis (PAM). The symptoms of PAM are indistinguishable from acute bacterial meningitis. Other amebae cause granulomatous amebic encephalitis (GAE), which is a more subacute and can even a non-symptomatic chronic infection. Ameobic meningoencephalitis can mimic a brain abscess, aseptic or chronic meningitis, or CNS malignancy.[5]


Animal pathogens exist as facultative parasites. They are an exceptionally rare cause of meningoencephalitis.[6]


The disease is associated with high rates of mortality and severe morbidity.

Notable cases

It was cause of death of the popular British TV presenter Christopher Price.[7]

In May, 2009 former Premier of New South Wales (Australia) Morris Iemma was admitted to hospital with meningoencephalitis.[8]

Recent medical research indicates that it was the cause of Mary Ingalls' (older sister of Laura Ingalls) blindness (not scarlet fever as the book indicates).[9][10][11][12]

In popular culture

In the 2011 film Contagion, the pandemic disease kills when it causes meningoencephalitis in patients. The film's virus is named Meningoencephalitis Virus One (MEV-1).

In the 'House' episode Euphoria (Part 2), primary amoebic meningoencephalitis was the cause of Foreman's symptoms.

See also


  1. ^ Bruyn HB, Sexton HM, Brainerd HD (March 1957). "Mumps meningoencephalitis; a clinical review of 119 cases with one death". Calif Med 86 (3): 153–60.  
  2. ^ Newton, PJ; Newsholme, W; Brink, NS; Manji, H; Williams, IG; Miller, RF (2002). "Acute meningoencephalitis and meningitis due to primary HIV infection". BMJ (Clinical research ed.) 325 (7374): 1225–7.  
  3. ^ Del Saz, SV; Sued, O; Falcó, V; Agüero, F; Crespo, M; Pumarola, T; Curran, A; Gatell, JM; et al. (2008). "Acute meningoencephalitis due to human immunodeficiency virus type 1 infection in 13 patients: clinical description and follow-up". Journal of neurovirology 14 (6): 474–9.  
  4. ^ Orgogozo JM, Gilman S, Dartigues JF, et al. (2003-07-08). "Subacute meningoencephalitis in a subset of patients with AD after Aß42 immunization". Neurology 61 (1): 46–54.  
  5. ^ Amebic Meningoencephalitis at eMedicine
  6. ^ "Rare parasitic worm kills two kidney donor patients, inquest hears". The Guardian. 2014-11-18. Retrieved 2014-11-24. 
  7. ^ "Presenter Killed by Rare Infection". BBC News. 2002-06-19. Retrieved 2008-05-01. 
  8. ^ Silmalis, Linda (2009-06-28). "Paralysed Iemma fights to walk again". The Sunday Telegraph. Retrieved 2009-06-28. 
  9. ^ Allexan, Sarah S.; Byington, Carrie L.; Finkelstein, Jerome I.; Tarini, Beth A. (2013). "Blindness in Walnut Grove: How Did Mary Ingalls Lose Her Sight?". Pediatrics. peds.2012-1438. 
  10. ^ Dell'Antonia, KJ (2013-02-04). "Scarlet Fever Probably Didn’t Blind Mary Ingalls". New York Times. Retrieved 2013-02-04. 
  11. ^ Serena, Gordon (2013-02-04). "Mistaken Infection 'On The Prairie'?". U.S. News and World Report. Retrieved 2013-02-04. 
  12. ^ "What really made Mary Ingalls go blind?". NBC News. 2013-02-04. 

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from World Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.